Blar i forfatter "Christakoudi, Sofia"

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    • Association between anthropometry and lifestyle factors and risk of B-cell lymphoma: An exposome-wide analysis 

      Hosnijeh, Fatemeh Saberi; Casabonne, Delphine; Nieters, Alexandra; Solans, Marta; Naudin, Sabine; Ferrari, Pietro; McKay, James D.; Benavente, Yolanda; Weiderpass, Elisabete; Freisling, Heinz; Severi, Gianluca; Ruault, Marie-Christine Boutron; Bonet, Catalina; Besson, Caroline; Agnoli, Claudia; Barricarte, Aurelio; Christakoudi, Sofia; Masala, Giovanna; Knuppel, Anika; Sacerdote, Carlotta; Bueno-De-Mesquita, Bas; Tumino, Rosario; Huerta, José María; Schulze, Matthias B.; Kaaks, Rudolf; Amiano, Pilar; Barranco, Miguel Rodriguez; Canzian, Federico; Späth, Florentin; Jerkeman, Mats; Rylander, Charlotta; Tjønneland, Anne; Olsen, Anja; Borch, Kristin Benjaminsen; Vermeulen, Roel (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-31)
      To better understand the role of individual and lifestyle factors in human disease, an exposome‐wide association study was performed to investigate within a single‐study anthropometry measures and lifestyle factors previously associated with B‐cell lymphoma (BCL). Within the European Prospective Investigation into Cancer and nutrition study, 2402 incident BCL cases were diagnosed from 475 426 ...

    • The association between body fatness and mortality among breast cancer survivors: results from a prospective cohort study 

      Bonet, Catalina; Crous-Bou, Marta; Tsilidis, Konstantinos K.; Gunter, Marc J.; Kaaks, Rudolf; Schulze, Matthias B.; Turzanski Fortner, Rénee; Antoniussen, Christian S.; Dahm, Christina C.; Mellemkjær, Lene; Tjønneland, Anne; Amiano, Pilar; Ardanaz, Eva; Colorado-Yohar, Sandra M.; Rodriguez-Barranco, Miguel; Tin Tin, Sandar; Agnoli, Claudia; Masala, Giovanna; Panico, Salvatore; Sacerdote, Carlotta; May, Anne M.; Borch, Kristin Benjaminsen; Rylander, Karin Charlotta Maria; Skeie, Guri; Christakoudi, Sofia; Aune, Dagfinn; Weiderpass, Elisabete; Dossus, Laure; Riboli, Elio; Agudo, Antonio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-29)
      Evidence linking body fatness to breast cancer (BC) prognosis is limited. While it seems that excess adiposity is associated with poorer BC survival, there is uncertainty over whether weight changes reduce mortality. This study aimed to assess the association between body fatness and weight changes pre- and postdiagnosis and overall mortality and BC-specific mortality among BC survivors. Our study ...

    • Body Size at Different Ages and Risk of 6 Cancers: A Mendelian Randomization and Prospective Cohort Study 

      Mariosa, Daniela; Smith-Byrne, Karl; Richardson, Tom G.; Ferrari, Pietro; Gunter, Marc J.; Papadimitriou, Nikos; Murphy, Neil; Christakoudi, Sofia; Tsilidis, Konstantinos K.; Riboli, Elio; Muller, David; Purdue, Mark P.; Chanock, Stephen J.; Hung, Rayjean J.; Amos, Christopher I.; O'Mara, Tracy A.; Amiano, Pilar; Pasanisi, Fabrizio; Rodriguez-Barranco, Miguel; Krogh, Vittorio; Tjønneland, Anne; Halkjær, Jytte; Perez-Cornago, Aurora; Chirlaque, María-Dolores; Skeie, Guri; Rylander, Charlotta; Borch, Kristin Benjaminsen; Aune, Dagfinn; Heath, Alicia K.; Ward, Heather A.; Schulze, Matthias; Bonet, Catalina; Weiderpass, Elisabete; Davey Smith, George; Brennan, Paul; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-19)
      It is unclear if body weight in early life affects cancer risk independently of adult body weight. To investigate this question for 6 obesity-related cancers, we performed univariable and multivariable analyses using 1) Mendelian randomization (MR) analysis and 2) longitudinal analyses in prospective cohorts. Both the MR and longitudinal analyses indicated that larger early life body size was ...

    • Dietary patterns related to biological mechanisms and survival after breast cancer diagnosis: results from a cohort study 

      Castro-Espin, Carlota; Bonet, Catalina; Crous-Bou, Marta; Katzke, Verena; Le Cornet, Charlotte; Jannasch, Franziska; Schulze, Matthias B.; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Antoniussen, Christian S.; Sánchez, Maria Jose; Amiano, Pilar; Chirlaque, María Dolores; Guevara, Marcela; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; De Magistris, Maria Santucci; Sund, Malin; Bodén, Stina; Jensen, Torill; Olsen, Karina Standahl; Skeie, Guri; Gunter, Marc J.; Rinaldi, Sabina; Gonzalez-Gil, Esther M.; Weiderpass, Elisabete; Christakoudi, Sofia; Heath, Alicia K.; Dossus, Laure; Agudo, Antonio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-03)
      Background - Inflammatory, insulin and oestrogenic pathways have been linked to breast cancer (BC). We aimed to examine the relationship between pre-diagnostic dietary patterns related to these mechanisms and BC survival.<p> <p>Methods - The diabetes risk reduction diet (DRRD), inflammatory score of diet (ISD) and oestrogen-related dietary pattern (ERDP) were calculated using dietary data from ...

    • Long-term weight change and risk of breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study 

      Ellingjord-Dale, Merete; Christakoudi, Sofia; Weiderpass, Elisabete; Panico, Salvatore; Dossus, Laure; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Schulze, Matthias B.; Masala, Giovanna; Gram, Inger Torhild; Skeie, Guri; Rosendahl, Ann H.; Sund, Malin; Key, Tim; Ferrari, Pietro; Gunter, Marc; Heath, Alicia K; Tsilidis, Konstantinos K; Riboli, Eilo; Sánchez, Maria-Jose; Lopez, Maria-Dolores Chirlaque; Peppa, Eleni; Trichopoulou, Antonia; Martimianaki, Georgia; Agudo, Antonio; Santiuste, Carmen; Ardanaz, Eva; Amiano, Pilar; Boutron-Ruault, Marie-Chiristine; Simeon, Vittorio; Berrino, Franco; Tumino, Rosario; Severi, Gianluca; Stocks, Tanja; Turzanski-Fortner, Renée; Rylander, Charlotta; Aune, Dagfinn; Dahm, Christina Catherine (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-23)
      Background: The role of obesity and weight change in breast-cancer development is complex and incompletely understood. We investigated long-term weight change and breast-cancer risk by body mass index (BMI) at age 20 years, menopausal status, hormone replacement therapy (HRT) and hormone-receptor status.<p><p> Methods: Using data on weight collected at three different time points from women ...

    • Mediating Role of Lifestyle Behaviors in the Association between Education and Cancer: Results from the European Prospective Investigation into Cancer and Nutrition 

      Macciotta, Alessandra; Catalano, Alberto; Giraudo, Maria Teresa; Weiderpass, Elisabete; Ferrari, Pietro; Freisling, Heinz; Colorado-Yohar, Sandra M.; Santiuste, Carmen; Amiano, Pilar; Heath, Alicia K.; Ward, Heather A.; Christakoudi, Sofia; Vineis, Paolo; Singh, Deependra; Vaccarella, Salvatore; Schulze, Matthias B.; Hiensch, Anouk E.; Monninkhof, Evelyn M.; Katzke, Verena; Kaaks, Rudolf; Tumino, Rosario; Lazzarato, Fulvio; Milani, Lorenzo; Agudo, Antonio; Dahm, Christina C.; Baglietto, Laura; Perduca, Vittorio; Severi, Gianluca; Grioni, Sara; Panico, Salvatore; Ardanaz, Eva; Borch, Kristin Benjaminsen; Benebo, Faith Owunari; Braaten, Tonje; Sánchez, Maria-Jose; Giachino, Claudia; Sacerdote, Carlotta; Ricceri, Fulvio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-09)
      Background: Many studies have shown that socioeconomic position (SEP) is associated with the incidence of malignant tumors at different sites. This study aims to estimate the association between educational level (as proxy for SEP) and cancer incidence and to understand whether the observed associations might be partially explained by lifestyle behaviors.<p> <p>Methods: The analyses were performed ...

    • Metabolically Defined Body Size Phenotypes and Risk of Endometrial Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Kliemann, Nathalie; Ammar, Romain Ould; Biessy, Carine; Gicquiau, Audrey; Katzke, Verena; Kaaks, Rudolf; Tjønneland, Anne; Olsen, Anja; Sánchez, Maria-Jose; Crous-Bou, Marta; Pasanisi, Fabrizio; Tin, Sandar Tin; Perez-Cornago, Aurora; Aune, Dagfinn; Christakoudi, Sofia; Heath, Alicia K.; Colorado-Yohar, Sandra M.; Grioni, Sara; Skeie, Guri; Sartor, Hanna; Idahl, Annika; Rylander, Charlotta; May, Anne M.; Weiderpass, Elisabete; Freisling, Heinz; Playdon, Mary C.; Rinaldi, Sabina; Murphy, Neil; Huybrechts, Inge; Dossus, Laure; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-01)
      Background: Obesity is a risk factor for endometrial cancer but whether metabolic dysfunction is associated with endometrial cancer independent of body size is not known.<p> <p>Methods: The association of metabolically defined body size phenotypes with endometrial cancer risk was investigated in a nested case–control study (817 cases/ 817 controls) within the European Prospective Investigation ...

    • Nutrient-wide association study of 92 foods and nutrients and breast cancer risk 

      Heath, Alicia K.; Muller, David C.; van den Brandt, Piet A.; Papadimitriou, Nikos; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Weiderpass, Elisabete; Fagherazzi, Guy; Boeing, Heiner; Ferrari, Pietro; Olsen, Anja; Tjønneland, Anne; Arveux, Patrick; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Kuhn, Tilman; Turzanski-Fortner, Renee; Schulze, Matthias B.; Karakatsani, Anna; Thriskos, Paschalis; Thrichopoulou, Antonia; Masala, Giovanna; Contiero, Paolo; Ricceri, Fulvio; Panico, Salvatore; Bueno-De-Mesquita, Bas; Bakker, Marije F.; van Gils, Carla H.; Olsen, Karina Standahl; Skeie, Guri; Lasheras, Cristina; Agudo, Antonio; Rodrigues-Barranco, Miguel; Sánchez, Maria-José; Amiano, Pilar; Chirlaque, María-Dolores; Barricarte, Aurelio; Drake, Isabel; Ericson, Ulrika; Johansson, Ingegerd; Winkvist, Anna; Key, Tim; Freisling, Heinz; His, Mathilde; Huybrechts, Inge; Christakoudi, Sofia; Ellingjord-Dale, Merete; Riboli, Elio; Tsilidis, Konstantinos K.; Tzoulaki, Ioanna (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-13)
      <i>Background</i> - Several dietary factors have been reported to be associated with risk of breast cancer, but to date, unequivocal evidence only exists for alcohol consumption. We sought to systematically assess the association between intake of 92 foods and nutrients and breast cancer risk using a nutrient-wide association study.<p> <p><i>Methods</i> - Using data from 272,098 women ...

    • Prediagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma 

      Stepien, Magdalena; Lopez-Nogueroles, Marina; Lahoz, Agustın; Kühn, Tilman; Perlemuter, Gabriel; Voican, Cosmin; Ciocan, Dragos; Boutron-Ruault, Marie-Christine; Jansen, Eugéne H.J.M.; Viallon, Vivian; Leitzmann, Michael; Tjønneland, Anne; Severi, Gianluca; Mancini, Francesca Romana; Dong, Catherine; Kaaks, Rudolf; Fortner, Renée T.; Bergmann, Manuela M.; Boeing, Heiner; Trichopoulou, Antonia; Karakatsani, Anna; Peppa, Eleni; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Skeie, Guri; Merino, Susana; Zamora-Ros, Raúl; Sánchez, Maria Jose; Amiano, Pilar; Huerta, José María; Barricarte, Aurelio; Sjöberg, Klas; Ohlsson, Bodil; Nyström, Hanna; Werner, Mårten; Perez-Cornago, Aurora; Schmidt, Julie A.; Freisling, Heinz; Scalbert, Augustin; Weiderpass, Elisabete; Christakoudi, Sofia; Gunter, Marc; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-29)
      Bile acids (BAs) play different roles in cancer development. Some are carcinogenic and BA signaling is also involved in various metabolic, inflammatory and immune-related processes. The liver is the primary site of BA synthesis. Liver dysfunction and microbiome compositional changes, such as during hepatocellular carcinoma (HCC) development, may modulate BA metabolism increasing concentration of ...

    • Prospective analysis of circulating metabolites and breast cancer in EPIC 

      His, Mathilde; Viallon, Vivian; Dossus, Laure; Gicquiau, Audrey; Achaintre, David; Scalbert, Augustin; Ferrari, Pietro; Romieu, Isabelle; Onland-Moret, N. Charlotte; Weiderpass, Elisabete; Dahm, Christina C.; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Fournier, Agnès; Rothwell, Joseph A.; Severi, Gianluca; Kühn, Tilman; Fortner, Renée Turzanski; Boeing, Heiner; Trichopoulou, Antonia; Karakatsani, Anna; Martimianaki, Georgia; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; van Gils, Carla H.; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Skeie, Guri; Quirós, José Ramón; Agudo, Antonio; Sánchez, María-José; Amiano, Pilar; Huerta, José María; Ardanaz, Eva; Schmidt, Julie A.; Travis, Ruth C.; Riboli, Elio; Tsilidis, Konstantinos K.; Christakoudi, Sofia; Gunter, Mark J.; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-24)
      <i>Background</i> - Metabolomics is a promising molecular tool to identify novel etiologic pathways leading to cancer. Using a targeted approach, we prospectively investigated the associations between metabolite concentrations in plasma and breast cancer risk.<p> <p><i>Methods</i> - A nested case-control study was established within the European Prospective Investigation into Cancer cohort, which ...

    • Prospective analysis of circulating metabolites and endometrial cancer risk 

      Dossus, Laure; Kouloura, Eirini; Biessy, Carine; Viallon, Vivian; Siskos, Alexandros P.; Dimou, Niki; Rinaldi, Sabina; Merritt, Melissa A.; Allen, Naomi E.; Fortner, Renée T.; Kaaks, Rudolf; Weiderpass, Elisabete; Gram, Inger Torhild; Rothwell, Joseph A.; Lécuyer, Lucie; Severi, Gianluca; Schulze, Matthias B.; Nøst, Therese Haugdahl; Crous-Bou, Marta; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Barricarte, Aurelio; Schmidt, Julie A.; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Mattiello, Amalia; Vermeulen, Roel; Heath, Alicia K.; Christakoudi, Sofia; Tsilidis, Konstantinos K.; Travis, Ruth C.; Gunter, Marc J.; Keun, Hector C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-05)
      Background. Endometrial cancer is strongly associated with obesity and dysregulation of metabolic factors such as estrogen and insulin signaling are causal risk factors for this malignancy. To identify additional novel metabolic pathways associated with endometrial cancer we performed metabolomic analyses on pre-diagnostic plasma samples from 853 case-control pairs from the European Prospective ...